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alex 2 -test  (MacroArray Diagnostics GmbH)

 
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    MacroArray Diagnostics GmbH alex 2 -test
    Alex 2 Test, supplied by MacroArray Diagnostics GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/alex 2 -test/product/MacroArray Diagnostics GmbH
    Average 90 stars, based on 1 article reviews
    alex 2 -test - by Bioz Stars, 2026-05
    90/100 stars

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    Clinical features. (A and B) Brain MRI (A) and colonoscopy (B) of P1. (C) Gross image showing colectomy specimen from P1 with diffuse pancolitis. (D) H&E stains, left (10× magnification), showing full thickness section of the distal colon with inflammation limited to the superficial submucosa and inflammatory pseudopolyps with lymphoid aggregates (arrows). The uninflamed muscularis propria and subserosa with congested vessels can be seen. (D) Center and right (200× magnification), showing lamina propria with numerous neutrophils and eosinophils accompanying two multinucleated giant cells, indicating a site of crypt rupture. (E) Colonoscopy of P2. (F) Image of P2 showing severe atopic dermatitis. (G) Screening <t>for</t> <t>IgE</t> against 295 allergens with the <t>ALEX</t> Allergy Explorer. (H) Eosinophil counts in whole blood ( n = 7), normal upper limit <0.5 × 10 9 /liter; and IgE concentrations ( n = 4), normal upper limit (IgE < 100 kU/liter) for P2 (red dots).
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    Clinical features. (A and B) Brain MRI (A) and colonoscopy (B) of P1. (C) Gross image showing colectomy specimen from P1 with diffuse pancolitis. (D) H&E stains, left (10× magnification), showing full thickness section of the distal colon with inflammation limited to the superficial submucosa and inflammatory pseudopolyps with lymphoid aggregates (arrows). The uninflamed muscularis propria and subserosa with congested vessels can be seen. (D) Center and right (200× magnification), showing lamina propria with numerous neutrophils and eosinophils accompanying two multinucleated giant cells, indicating a site of crypt rupture. (E) Colonoscopy of P2. (F) Image of P2 showing severe atopic dermatitis. (G) Screening <t>for</t> <t>IgE</t> against 295 allergens with the <t>ALEX</t> Allergy Explorer. (H) Eosinophil counts in whole blood ( n = 7), normal upper limit <0.5 × 10 9 /liter; and IgE concentrations ( n = 4), normal upper limit (IgE < 100 kU/liter) for P2 (red dots).
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    Clinical features. (A and B) Brain MRI (A) and colonoscopy (B) of P1. (C) Gross image showing colectomy specimen from P1 with diffuse pancolitis. (D) H&E stains, left (10× magnification), showing full thickness section of the distal colon with inflammation limited to the superficial submucosa and inflammatory pseudopolyps with lymphoid aggregates (arrows). The uninflamed muscularis propria and subserosa with congested vessels can be seen. (D) Center and right (200× magnification), showing lamina propria with numerous neutrophils and eosinophils accompanying two multinucleated giant cells, indicating a site of crypt rupture. (E) Colonoscopy of P2. (F) Image of P2 showing severe atopic dermatitis. (G) Screening <t>for</t> <t>IgE</t> against 295 allergens with the <t>ALEX</t> Allergy Explorer. (H) Eosinophil counts in whole blood ( n = 7), normal upper limit <0.5 × 10 9 /liter; and IgE concentrations ( n = 4), normal upper limit (IgE < 100 kU/liter) for P2 (red dots).
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    Image Search Results


    Clinical features. (A and B) Brain MRI (A) and colonoscopy (B) of P1. (C) Gross image showing colectomy specimen from P1 with diffuse pancolitis. (D) H&E stains, left (10× magnification), showing full thickness section of the distal colon with inflammation limited to the superficial submucosa and inflammatory pseudopolyps with lymphoid aggregates (arrows). The uninflamed muscularis propria and subserosa with congested vessels can be seen. (D) Center and right (200× magnification), showing lamina propria with numerous neutrophils and eosinophils accompanying two multinucleated giant cells, indicating a site of crypt rupture. (E) Colonoscopy of P2. (F) Image of P2 showing severe atopic dermatitis. (G) Screening for IgE against 295 allergens with the ALEX Allergy Explorer. (H) Eosinophil counts in whole blood ( n = 7), normal upper limit <0.5 × 10 9 /liter; and IgE concentrations ( n = 4), normal upper limit (IgE < 100 kU/liter) for P2 (red dots).

    Journal: The Journal of Experimental Medicine

    Article Title: Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis

    doi: 10.1084/jem.20240546

    Figure Lengend Snippet: Clinical features. (A and B) Brain MRI (A) and colonoscopy (B) of P1. (C) Gross image showing colectomy specimen from P1 with diffuse pancolitis. (D) H&E stains, left (10× magnification), showing full thickness section of the distal colon with inflammation limited to the superficial submucosa and inflammatory pseudopolyps with lymphoid aggregates (arrows). The uninflamed muscularis propria and subserosa with congested vessels can be seen. (D) Center and right (200× magnification), showing lamina propria with numerous neutrophils and eosinophils accompanying two multinucleated giant cells, indicating a site of crypt rupture. (E) Colonoscopy of P2. (F) Image of P2 showing severe atopic dermatitis. (G) Screening for IgE against 295 allergens with the ALEX Allergy Explorer. (H) Eosinophil counts in whole blood ( n = 7), normal upper limit <0.5 × 10 9 /liter; and IgE concentrations ( n = 4), normal upper limit (IgE < 100 kU/liter) for P2 (red dots).

    Article Snippet: Quantification of IgE levels against 295 allergens was performed on frozen plasma samples with ALEX Allergy Explorer Test System (Eurofins Biomnis).

    Techniques: